Which burns fat faster — fasting or Ozempic?
In this eye-opening interview, weight loss expert Dr. Jason Fung breaks down the truth about intermittent fasting and Ozempic (semaglutide) for fat loss. Are these weight loss injections worth the hype, or is there a safer, more natural alternative?
Dr. Jason Fung, Weight Loss Expert
🔥 Discover:
- Why Ozempic might not be a long-term solution
- The surprising benefits of fasting backed by science
- How hormones—not calories—control your body fat
- What most doctors won’t tell you about sustainable fat loss
Dr. Fung, author of The Obesity Code, shares real-world results, success stories, and science-based insights that challenge everything we think we know about burning fat. 💥 Whether you’re considering GLP-1 drugs or looking for a natural fat-burning strategy, this video will change the way you see weight loss.
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Will FASTING Burn Fat Faster than OZEMPIC? Dr. Jason Fung, Weight Loss Expert
Transcript
Ozempic is the American name, and these are all in a class called GLP-1s. They essentially really reduce appetite, which just goes to show, and people lose weight—lots of weight. Weight loss injections like Ozempic and Monaro promise shockingly big results from a small needle. But what if the ancient practice of fasting is not only safer but more effective? If losing weight is important, then just set aside a period of time when you don’t eat and let your body eat your body fat. That’s what fasting is doing, and it’s totally natural—body fat is not there for looks; it’s a source and store of calories. Fasting just lets you use that.
World’s number one weight loss expert, Dr. Jason Fung, puts modern medicine head-to-head with our metabolic biology to find out what really works and why—the answer will probably shock you. In academic centers, they all think about calories: how to get calories down, how to reduce calories. But it’s not about the calories; it’s about fixing the hormones behind the calories.
This isn’t just another health debate. We’re comparing the most hyped modern drug with the most ancient healing practice. One costs thousands; the other is free. One is prescription only; the other you can start today. GLP-1 agonists like Ozempic promise dramatic fat loss. But the lesson isn’t about controlling calories, because they don’t burn any calories. It’s about controlling your hunger, going deeper to why you’re taking in so many calories. If you simply reduce hunger, you naturally eat fewer calories and lose weight. That’s what Ozempic does: it really reduces appetite to very low levels. Users report less hunger, smaller portions, and massive sudden weight drops—even Elon Musk credits them. But is suppressing appetite enough for real, lasting change?
Fasting isn’t a fad—it’s hardwired into our biology. Fasting actually activates the body. Consider, as a caveman or cavewoman in winter with nothing to eat: if your body started to shut down, evolutionarily you’d die, with less energy and unable to hunt. Our bodies aren’t that stupid. Instead, they give more energy and change where it comes from. You stop getting energy from food and start drawing from body fat stores, which is just stored food. Dr. Jason Fung brought this back into the spotlight, not just as tradition, but as a metabolic weapon. Fasting doesn’t suppress appetite—it resets it.
Fat loss drugs send signals to your brain to eat less. That’s how Ozempic works, reducing appetite to very low levels. How? Through the hormone GLP-1, which is released mostly in the distal intestine and small intestine in response to certain foods. When you eat, the body has a homeostatic mechanism. People think we just eat uncontrollably, but when you eat, you activate GLP-1 and other hormones to tell you to stop eating—a feedback loop. Homeostasis keeps things at a proper level; GLP-1 is the one we’re interested in. When activated, it triggers the instructions to stop eating. The act of eating sets in motion the feedback loop to stop. These drugs mimic GLP-1, which tells your body “I’m full.”
Fasting, on the other hand, triggers your natural fat-burning mode. Insulin drops, growth hormone rises. For decades we’ve been told to eat less, move more. But if you eat fewer calories, your body burns fewer calories too. We’ve seen it in almost every single study. Eat fewer calories, body burns fewer calories—so eating 500 less means burning 500 less and not losing any body weight. The “eat less, move more” advice is outdated. Dr. Fung calls out the calorie model as broken and introduces hormones as the real culprit. Why can’t you burn fat that’s on your body, even if you have hundreds of thousands of calories stored? Because you haven’t activated the right hormones.
If you eat the wrong foods and eat all the time—even ten times a day, or on low-fat, high-carb diets—you spike insulin, which prevents fat burning. We’ve known this for 80 years. Eating 1,500 calories but keeping insulin high means you can’t burn body fat. The energy in fat cannot be accessed—it’s like money in a bank when the bank is closed.
Fasting builds resilience, while drugs may build dependency. GLP-1s help with digestion, increase insulin response, and then go to the brain, crossing the blood-brain barrier to the area that tells you to stop eating. These drugs give the hormone that says stop eating—even though you haven’t eaten. So, people report not being hungry and therefore don’t eat. When they don’t eat, insulin falls, calories are burned, and weight is lost. However, Ozempic users often regain weight when they stop because the root problem—hormone imbalance—hasn’t been fixed. It’s about controlling hunger, not just calories.
Successful weight loss drugs are hormone-based because those are the body’s instructions. Metabolism isn’t broken by fasting. Some claim fasting makes you eat more later, increasing hunger or lowering basal metabolic rate, leading to “starvation mode.” This myth is refuted by studies: for example, patients fasted for four days burn more calories on day four than on day zero. Basal metabolic rate increases, not decreases; fasting actually boosts metabolism short term, while reliance on drugs may downregulate natural hunger signals.
Who loses more fat? Ozempic curbs hunger, but fasting flips your metabolic switch. You can fast for 16 hours by eating breakfast later or dinner earlier, do a 24-hour fast, eat in a 6-hour window, eat once daily, or even go multiple days without food. The body knows what to do: even if your body has 100,000 calories stored and you fast three days (using just 6,000 calories), it draws from fat stores—let your body eat your body fat. After 16 hours fasting, stored fat is tapped, with no insulin in the way, making fat loss the default instead of a struggle.
Intermittent fasting allows insulin to fall, and when you fast, and insulin drops, your body draws from stored calories. Eating 1,500 calories with low insulin lets your body burn more fat. Dr. Fung’s patients have reversed diabetes, lost over 50 pounds, and normalized blood sugar without pills—just fasting. One patient’s weight dropped from over 250 to 210 lbs; waist size and A1C stabilized; insulin prescriptions dropped from 55 units to zero in six weeks.
These aren’t hacks; they’re long-term transformations. Another patient quickly lost 20 lbs, and at her three-month checkup, her A1C was 5.5%, within normal range and not diabetic. She also went off all medications as soon as she started fasting.
Fasting is free; fat loss drugs can cost over $1,000 monthly. So why is one pushed more than the other? “Follow the money.” There are lots of myths about fasting causing weight gain, fatigue, and hunger, but there is two thousand years of data showing fasting works safely. Dr. Fung began speaking out about fasting, facing criticism from doctors, dietitians, and others worried about harm, but colleagues admitted that during medical training, they regularly went 24 hours without food, with no problems.
You can’t sell a fast, but you can sell a shot. Autophagy—a process boosted by fasting—was awarded the 2016 Nobel Prize in Medicine for its importance. When fasting, autophagy breaks down and recycles subcellular organelles inside cells; this may sound bad, but it’s very good for you. Fasting helps your body clear out old, junky proteins, and growth hormone levels skyrocket, helping build new proteins once eating resumes. Fasting rejuvenates cells, enabling your body to get rid of the old and bring in the new.
If quick fixes are what’s needed, drugs deliver. But if the goal is root-cause healing that’s free and powerful, fasting wins every time. Let’s work together to become healthier not through drugs or surgery, but by using the tried and true—fasting. Fasting rewires hormones; drugs only rewire habits for a while. Dr. Fung also shares which five special foods to eat with intermittent fasting to cement weight loss success.
